I have always used anti-seize on spark plug threads, I have never had a problem. Be it GM, Ford, Jag, Toyota, Volvo, Mercruiser, or MB.

I wouldn't go nuts and dip the entire plug in but a light coating works like a charm.

The problem is the heads are aluminum and the plug threads are steel so they corrode in place. Be carefull or the threads will come out with the plug!

Get a 3/8 drive or if you have the room 1/2 is even better. Also spray the plugs with a good oil like PB Blaster, that usually helps stuck ones along.

FYI thats why their is a time and mileage intervial for changing plugs. Most of the new platnium plugs are 100k miles or 4 years. The reason they say 4 years is so you can get them out of the heads without stripping the threads.

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1999 SL500
1969 280SE
2023 Ram 1500
2007 Tiara 3200