Just want to say that my 96 W210 with the M104 engine has been reliable and I've not had any transmission problems on it. It currently has 203K miles and still drives very nice. As for Lexus, I've had 2 of them and both have been pretty reliable as well. The first had over 100K miles without any problems when it got totaled in an accident. I still have the second Lexus with over 225K miles with no problems. I do believe that preventative maintenance and how you drive the car has a lot to do how reliable a car is. Hope that the new G will be trouble free for you.

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2010 W212 E350 Sport
1996 W210 E320 (220K miles)