Yes, change the oil if you run a concentrated dose of Techron.
Best way to do it is wait till it is almost empty, put in the Techron and fill with some gas. There are several different size of Techron available but to be effective, you need a concentrated dose. The smaller bottle for 5 gallons of gas, for example.
Then, if possible, drive on some hiway but do not drive it dry. Shut down and let the system hot soak. Then drive again to almost and refill. Change the oil.