Consider check for vacuum leaks, and then your next step would be adjusting the mixture. I would also put a can of BG44K injection cleaner in the fuel tank (buy it on ebay) and then take it out on the road for an hour.
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1966 W111 250SEC:
DB268 Blaugrün/electric sunroof/4 on-the-floor/4.5 V-8 rear axle
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