Hunh. Never had any engine problems with the Izusu's. Couldn't keep brakes and front wheel bearings on the NPR series. Hated those danged "bicycle" tires ours came equipped with (215/70 R19.5's or some such oddball size). Switched them over to 225/70R19.5's and seemed to solve a lot of the problems.
I did stay pretty much on top of the servicing of the engines. Used Delo 400 15W40 exclusively. Dont know if that made any difference or I just got lucky.
Good trucks, or at least I had good luck with them, considering they drove like a flat bottomed barge.
(Dang it! ISUZU, ISUZU, ISUZU, oh hell, I'll never remember....)