Hit and miss.

They did away with SBC in 07, which is a big plus for reliability, but some still have airmatic (which can be a headache) and some have the 7 speed auto (which a few of the early ones had issues). If you can find an 09 E350 with no airmatic, it should be a rock solid car.

__________________
-Justin

91 560 SEC AMG - other dogs dd
01 Honda S2000 - dogs dd
07 MB ML320 CDI - dd
16 Lexus IS250 - wifes dd

it's automatic.