I am on week 12 of home brew B-100. (85 300D) It runs better, is peppier without doubt, but fuel economy has dropped to 19-21. (from 22-24)
I have been watching my lines and filters but so far no issues. (I am knocking on wood) My good results are on un-washed fuel. I would think that with the certified fuel grade stuff you get at the pumps would be no worry at all.
It's very nice filling up for 85-90 cents per gallon. Its going to be tough when it gets cold out to go back to diesel fuel.

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1959 Gravely LI, 1963 Gravely L8, 1973 Gravely C12
1982 380SL
1978 450 SEL 6.9 euro restoration at 63% and climbing
1987 300 D
2005 CDI European Delivery
2006 CDI Handed down to daughter
2007 GL CDI. Wifes