Inline vs. V6

I have a W124 model, the 1991 300CE, an inline 6 engine. I've always wondered what are the advantages or disadvantages of the inline 6 versus the V6. I realize that the size and shape of the engines are different, but I'm more interested in learning the performance differences.

Does one engine have a strength in one area but weaknesses in others? Is there a difference in performance at all?

Thanks.

Phil