My Benz is a 1989 300E with about 117,000 miles. Occasionally it feels like it is running out of gas or starving for gas. This happens most often when cold and accelerating right after starting but does sometimes happen on the highway usually after a sustained period of 70 mph (maybe a teeny bit more) and then decelerating. Last weekend I was on the highway and had the cruise set for 72. I slowed to about 50 and for the next 10 minutes or so, the car wouldn't accelerate normally. It eventually goes away but obviously something is wrong and I would like to fix it. Any ideas?? The first time this happened on the highway, I immediately replaced the fuel filter and it seemed better but has started to reoccur. It wasn't that long ago so I don't know that the filter had anything to do with it.
Thanks for the help.

Robi;
Sounds like fuel starvation alright!
Change the fuel filter first, if the problem persists then replace the pump(s)
M.f.

My car (85 190E2.3) has a similar problem. It was very pronounced earlier - then the oxygen sensor was changed, and that smoothed it out 90%. But a little bit still remains. BTW, all standard culprits have been changed - cap/rotor, plugs, wires, injectors, filters, etc. One tech said its the mass air sensor - haven't gotten it changed yet as the problem has drastically reduced with the new oxygen sensor.

Hence I am curious to know the cause of this problem in your case - maybe it can help me solve my problem! BTW, is your gas mileage OK? Mine had dropped, but is back to almost normal with the new O2 sensor.