MikeM, the 37 mm offset is ok if the new wheel width is still about the same. I believe the OEM wheel is 16x7.5.
Why downgrade to a C-Class wheel when there are so many nice E-Class wheels to consider? I think the AMG Monoblock in size 17x7.5 is really nice for W210 models. If you do not want to go Plus 1 check out the OEM 5-spoke wheel found on the 97 E420 and the 98-99 E430 in size 16x7.5.
By the way the car's price is now $35k!
www.statusimports.com/e430.html