In short, you only need a screwdriver and a wrench to perform the entire operation. The fan shroud is attached and removed without tools, and the rad is held in place by a couple of metal clips that you pry off (with the same screwdriver you use to loosen the clamps on the two hoses). The rad sits on two round slots on the front body frame, and just lifts right out.
The wrench is for loosening the metal hose to the transmission cooler, which is part of the rad.
This was the first real MB repair I've done, and it took me about two hours total. Removed the old one in about 1 1/2 hours...was so tickled that I got that far in such a short period of time that I celebrated with a beer and left the remainder of the work for the next day. Installed the new one, added coolant, and had the engine fired up within a 1/2 hour that evening.
You'll be surprised at how easy it is to do!
Go for it!