I left it off once and drove from Detroit to Kalamazoo....about 2 plus hours... no worries about getting rust in the engine compartment. It was about a half quart below the add mark IIRC.
doh!
(It's better than leaving off the drain plug.....I've done that too but never driven with that one off, just oiled my shoes a bit).
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[SIGPIC] Diesel loving autocrossing grandpa Architect. 08 Dodge 3/4 ton with Cummins & six speed; I have had about 35 benzes. I have a 39 Studebaker Coupe Express pickup in which I have had installed a 617 turbo and a five speed manual.

[SIGPIC]
..I also have a 427 Cobra replica with an aluminum chassis.