Yes. Mercedes actually has pre-drilled holes in the door and the wooden door card itself, so there are no modifications at all. Perhaps the most you will have to do away from factory specs is to punch a little hole in the vinyl for the crank to go through!

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[GONE] - 1995 Mercedes E300 Diesel - 130k miles - Smoke Silver (702) over Mushroom leather (265) - Bladder blasting, coast-to-coast work machine.