Sounds like you have some painting experience so I won't add much. I've done a TON of paint and body and have some schooling on it. About the only thing I'd add is to use the PPG DP series epoxy primer in the number (color) that works with your base coat - DP90 for example is black. Anyhow, if you thin it according to the instructions with lacquer thinner it makes an EXCELLENT sealer and pretty much blocks anything under the base from attacking the base or the clear.

Spray the base a little bit dry. I'm used to enamel which has to be sprayed just perfectly wet (too dry = orange peel, too wet = runs) so I tend to want to spray the base wet. If you do that it sometimes will bubble or wrinkle as subsequent layers trap the escaping solvents. So a little dry, mist the first coat of clear then have at it - wet, smooth, and shiney.

Dan