I have been burning every combination of fuel know to man over the past several years.
First motor will burn straight but it can be difficult to start below 20 degrees. You can try adding mineral spirits or diesel to thin it out .
As of recent I have been burning used canola oil straight , also dumping in used atf and motor oil. Every so often you really should burn a tank of diesel.I believe a long diet might soot up in the pre chambers and I say might.
The filtering process is quite simple. A 20 gallon parts washer tank and a oil furnace filter recirculated for about 24 to 48 hours. The dirty oil longer. I now am setting up a simpler filter that is similar to the fuel filter. This will be a second step after the first.
Synthetic oil burns the same as anything else.
Never had any problems with pumps, injectors, gelling, starting, smell, or smoke.
Go for it.