Yes because you will already have: Fuel pump package with proper lines/hoses and fittings, Proper Differential, Proper speedo (No tach on us market 280E sadly), Exhaust?. Also the title will say that it's a gasoline car with 6 cylinders so you won't have to get into all the red tape of trying to change that.

Also you will have another M110 for spare parts etc... to keep your swap going

The 280E was sold here 1977-1981. It made 140hp in stock US form. Had the same fuel injection but was low compression.