I don't know any of the technical info for you CLK. But if it's a cabriolet 6 speakers, and if it's a coupe, then 8 speakers.
You cannot change the speakers if you intend on keeping the factory head unit and amp. It will not work properly, and you could blow them very easily. I believe Mercedes uses 4 ohm speakers, and the usual is 6 or 2 ohms, the 4 being very hard to find. (Correct me if I am wrong anyone)
If you want more punch, I would suggest adding an amp and sub. I have a 400 watt amp (bypassing original amp) and a 10 inch sub. It sounds great now!