Odd Transmission question

[96C280]

I don't think anyone has asked the following:

Can the 722.6 (5 speed) be installed on a 96 c280 with little or no modification? I ask this because I know the 96 was the last year with the 722.4 while the 97 switched to the 722.6. However I also know the 97 was the last year the inline-6 104 was used before switching to the V-6 in 98. I figure that was a pretty good combination, especially after the bugs of the 722.6 were worked out. I ask this because in the future, if I ever have to replace the trans.... Were there chassis changes/mounting changes for the new tranmission?