On my 1996 SL600, the center compartments (armrest, rolltop box), as well as the rear shelf compartments lock. The map compartments and other compartments dont lock.

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-Justin

91 560 SEC AMG - other dogs dd
01 Honda S2000 - dogs dd
07 MB ML320 CDI - dd
16 Lexus IS250 - wifes dd

it's automatic.