I would start with the three coil connectors. They are notorious for misfires.

Also check to see if you are running copper core OEM non-resistor plugs.

Do a search for Arthur Dalton's posts. He is a treasure trove of information for your car.

__________________
Paul S.

2001 E430, Bourdeaux Red, Oyster interior.
79,200 miles.

1973 280SE 4.5, 170,000 miles. 568 Signal Red, Black MB Tex. "The Red Baron".