2000-2006 are the darkest years for Mercedes Benz build quality and quality control, so if you must have one from that time envelope, only buy it as certified pre owned from a dealer, and get the longest, best, and most comprehensive factory warranty you can - chances are VERY good you will be making lots of claims on it.

__________________
1991 560 SEC AMG, 199k <---- 300 hp 10:1 ECE euro HV ...

1995 E 420, 170k "The Red Plum" (sold)

2015 BMW 535i xdrive awd Stage 1 DINAN, 6k, <----364 hp

1967 Mercury Cougar, 49k

2013 Jaguar XF, 20k <----340 hp Supercharged, All Wheel Drive (sold)