One of the pumps on my 560SEC would overheat and shut off while driving, due to an almost completely clogged fuel filter. The car would all of the sudden have no power, and would idle very roughly. Not sure if that was because it was only running on one pump, or because of the clogged filter. Guess it doesn't really matter? lol. Replaced both pumps and filter, and all was fine. Although a while after I sold it, the new owner told me the fuel filter had clogged again. So change those filters regularly!

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Current cars:
2000 ML55 AMG, 174k miles
2003 C240 T-Modell, 202k miles
1995 S320, 207k Miles