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Front or rear brakes? On a 560SEL you do not need to remove the caliper to replace the pads. Remove the two pins holding the pads in at the back, and the spring clip will come off too, then compress the pistons in, pull the old pads out, clean up the caliper, lube up the back of the new ones with anti-seize, shove them in, put the pins and clip back in place, and you're done!
No need to remove the caliper. And no, the parking brake being on would not affect removal of the caliper.
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'13 ML350 Bluetec - 95k - dad's (OC-98k)
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