That strip holds the window felt. It ca either stay or come off with the panel. It's held on to the car with metal clips. If it stays you'll have to put the panel under it carefully (PITA). If it comes off with the panel you'll have to tap the clips back into place. No Biggy

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'70 F100 shortbed
'82 Diesel Westy
'83 Euro 300TD
Curtlo Viper
Yeti ARC
Surly long haul trucker