Great cars, my dentist has owned his 2000 S430 since new and hasn't had to much trouble with it. I think he said a coil went bad a few years ago, I think he has about 130k on it now.

It seems to be at his mechanics about as often as his wife's SDL.

Just don't buy a shot one with a million miles on it, buy something pretty new and decent, I'd look 2005+. MB also offered the S350 for one year. Based on my friends experience with his 02 G500 it seems 2000-05 was a bit iffy electronics wise for MB. After that they seem to be pretty solid, no one I know with the newer ones ever seems to complain.

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2016 Corvette Stingray 2LT
1969 280SE
2023 Ram 1500
2007 Tiara 3200