If you are a little more technically inclined I use a SANS Digital enclosure.
http://www.tigerdirect.com/applications/SearchTools/item-details.asp?EdpNo=6637381&CatId=2780
eSATA, although I paid like 160 just a couple of months ago.
I run it as 4 independent drives.
Not a huge believer in consumer level RAID, I have heard good things about DROBO though.
I did pay less, this one is eSATA only
http://www.tigerdirect.com/applications/category/category_slc.asp?MfrId=2672&Nav=|c:2780|&Sort=0&Recs=10