Hi there...
I had to replace the speakers on my 90 300e. Actually I wanted to anyway as the origionals were 12 years old and not that great to begin with. It can be tricky but once you know the tricks its really not that bad. If you are going to have Circuit City or someone like that do it for you...
Make darn sure thay have done MB 300's before. There are many parts they can break while running wires if they don't know what they are doing!
I just finished mine this past month and I really learned alot about the 300 doing it.
http://www.peachparts.com/shopforum/showthread.php?threadid=47787
Happy to help if I can.
Good Luck!
Steve