My take on the ML Class is that they will be costly vehicles to own and drive any amount of mileage.

The 05/06 CDI E320s have their own weak points, but I've yet to experience any transmission troubles with any MB diesel car I've owned or had in our family. Of course luck, care and maintenance may have had something to do with it, but all of our cars were either bought new, or had been in the highly desirable category of very well kept, somewhat new when we bought them.

Transmissions don't even register on my worry-index with their solid 45 years and running reputation with me.

If you're looking to save money on an ML for your transportation needs in an AWD, frankly, unless you're willing to spend a lot of money on it, I would go to another brand.

The E320 CDIs will cost you money to keep on the road too, there's no question about that either, but they're not to be compared to the higher cost(s) related to the ML series to do the same.

I would go over whatever I bought with a fine tooth comb before buying as to it's history/care/and condition.

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'06 E320 CDI
'17 Corvette Stingray Vert