These cultural/genetic isolate populations are fascinating.

The founder effect is quite pronounced in Anabaptist populations. For example, most of the more than 40,000 Hutterites in North America can trace their ancestry back to a group of 89 founding members (2). Small founding populations and isolation result in genetic homogeneity and can greatly skew the prevalence of certain genetic disorders, particularly autosomal recessive conditions (4).

Amish, Mennonite, and Hutterite Genetic Disorder Database

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