This sounds most likely like a communication issue, because both are out at the same time.
Or simply a bad brake light switch?
Or bad brake light assembly contacts? Read Dspicher's post, very interesting.
https://forums.edmunds.com/discussion/5796/mercedes-benz/r-class/mercedes-benz-r-class-electrical-problems
Does the IcarSoft MB really say "Open or Short" if so.
If it where a true open you'd have 12v at the beginning of the brake light circuit, but 0v at the bulb.
If where a true full short to ground it would read 0v at the source (where the circuit begins) and 0v at the load.
That's all I can think of.