Are you referring to the cam bearings not lining up or the journal/lobes?
I have two different M110 engines in my shop.
One is a 1978 W116 280SE and the other is from a 1973 280.
There is a difference in the cam boxes.
1978 W116 280SE:
1973 W114 280:
Note the difference of the cam bearings. The '78 fuelie has 5 bearings on the intake cam and 6 on the exhaust.
The '73 (carb'ed) has 7 bearings on the intake and 8 on the exhaust.
Don't know whether it is due to model year differences or injection vs. carburetion. I suspect it is due to injection but I've been wrong before.