Star Tron (starbrite) fuel additive for diesels is supposed to have an enzyme that breaks up anything growing inside of your fuel tank into particles small enough to pass through your filters.
However, it is still a good idea to keep a few filters in the trunk just in case the die off overwhelms the filter.
"Known as "diesel algae" these are primarily
fungi, yeast and mold contaminants. If left
untreated, diesel algae will ruin the fuel
causing clogs in filters, fuel lines and injectors.
Common treatment for this problem up until
now has been the use of a biocide to kill
existing growth and prevent a future
infestation. The use of a biocide can however
cause other problems. Once the growth is
killed, the resulting biomass settles to the tank
bottom where it decays forming organic acids.
The acids then deteriorate the fuel and cause
corrosion of the tank walls, injectors and fuel
delivery system. Additionally, biocides can be
harmful to all those who handle them or come
in contact with treated fuel, plus they can
cause environmental damage if spilled. Star
TronŽ uses its enzyme technology to disperse
microbial growth throughout the fuel. These
microbial particles are then either safely
burned away or filtered out."
Reading further it goes on to speak of water in the fuel.
https://defender.com/assets/pdf/star-brite/startron_story.pdf