Sure. You can run kerosene in it if you can get it to burn the stuff. You have a knock sensor that will retard the ignition timing if it detects spark knock to prevent engine damage.

That said, under most driving conditions this is false economy. When the ignition is retarded, the fuel mileage will decrease, negating at least some of your fuel savings.

The difference in cost between the three fuel grades is the same regardless of the gas prices. Premium is always about 20 cents higher than regular and about 10 cents higher than mid grade. That means that at $1 per gallon it is about 20% more expensive, but at $2 per gallon it is only about 10% more expensive.

You have a car that cost well over $40,000 new and has a high compression ratio. By running mid grade your performance and your fuel mileage will degrade. Spend another 10 cents per gallon and be done with it IMHO.

Good luck,