Well, I was hoping for more of a layman's approach. So following common sense, here's what I did:

I turned the wheels all the way to the left, and adjusted the screw CCW until it seated, I then backed it off about 1/8 of a turn. I then turned the wheels all the way to the right and checked it again, then in the center.

I then took it for a road test and I wasn't happy with the feel. It felt a bit tight and didn't self center anymore. So I backed off the screw CW another 1/8th. Road testing again, it was better, but still not quite right, - so another 1/8th. Then life was good.

By the way, the play in the wheel didn't change at all, with the screw seated, or backed off 1/2 a turn, it was still about an inch.