Not too much of a problem if you are towing across level ground or moderate hills, but your trailer and load is a bit heavy for mountain climbing, for the car.

Also, I'm not sure there's all that much advantage to running in something other than the normal "D" on regular ground - these cars are geared on the low side. It's a 4-spd transmission, not a 3-spd with overdrive.

Ken300D

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1982 300D at 351K miles
1984 300SD at 217K miles
1987 300D at 370K miles