My driver and passender seat electric adjustments work sometimes, sometimes not. There doesn't seem to be a pattern when they will start to work, any ideas?

Thanks

Yes. Search on "C280 seats"

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1998 C230 330,000 miles (currently dead of second failed EIS, yours will fail too, turning you into the dealer's personal human cash machine)
1988 F150 144,000 miles (leaks all the colors of the rainbow)
Previous stars: 1981 Brava 210,000 miles, 1978 128 150,000 miles, 1977 B200 Van 175,000 miles, 1972 Vega (great, if rusty, car), 1972 Celica, 1986.5 Supra

There is a relay in the trunk that supplys power to the seat fuses.
Most likely your problem.

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MERCEDES Benz Master Guild Technician (6 TIMES)
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190E 2.3 16V ITS SCCA race car (sold)
1986 190E 2.3 16V 2.5 (sold)
Retired Moderator

I will investigate the relay.