I think 4Matic only comes with the C320 and C350. The M112 is just about bulletproof. Some (early?) M272s had balance shaft i$$ues. Watch out for ‘06 to mid ‘07 E350s. Once fixed it’s ready for a long life. ‘03 to ‘05 E320s have SBC which is essentially a brake assist pump good for so much time on the pedal. It’s a ~$1,000 part that can be DIY replaced if you have access to SDS. I don’t know what shops charge to change an SBC pump but it’s gotta be in $2,000 range. The. You’re good for another 10 years or so.

I’d be less concerned with miles than condition. A 120K mile car that’s well cared for could trump an 80K mile car of unknown provenance.

Sixto
98 E320s sedan and wagon