To add to my above reply from last year....
I had a 1985 380SE with 276K miles with the original drivetrain. Engine still ran well (occasional stalling on turns, which the MB tech said was leaking injectors), but was starting to get a knock (worn out camshaft)... the original transmission still shifted perfectly, except it would slam into reverse. I also think my timing chain tensioner/guides and rails, etc were wearing out big time. Save for the dash, the interior was still like new and everything worked perfectly. I sold it to a local guy for $650. He was going to paint it and install new timing chain and parts.
I will never forget - one big issue with that car was "scrunching" door panels. The guy that bought it even commented on it. At the time, I did not know that placing velcro strips on the bottoms of the door panels would eliminate it. Oh well. Strange, the car did not have any squeaks or rattles though.