As Frank has mentioned play in the pinion bearings will cause changes in whine when driving with (abrupt) changes in accelerator position.
If this is happening then it is probably time to get the differential rebuilt.
There are a few things I can think of that might help however but these are rather short term fixes.
As a matter of interest - I assume you've got the larger casing differential fitted (as the rest of your estate parts are on the beefier side)
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