Request for help re: LA Thanksgiving traffic patterns

[Shortsguy1]

My family and I are going to be driving from San Luis Obispo to Redlands, CA (east of Los Angeles) for Thanksgiving. We have two small kids (1 yo and 3 yo), so even the normal 4 hour version of this drive is difficult. We need to leave on Wednesday and I am trying to figure out what time to leave SLO to avoid too much evening/night traffic when we get to Los Angeles. We plan to take the most direct route: 101S, 134, 210, and finally I-10.

Does anyone know what time the gridlock associated with the Wednesday before Thanksgiving might clear in LA?

It takes us about 3 hours to get from SLO to LA. We are basically trying to decide to leave at 6 PM, 7 PM, or 8 PM. Do you think the traffic will still be awful in LA at 9 PM, 10 PM, or 11 PM?

Thanks for any suggestions.