I have the same issue with our Honda Odyssey. I traced the drain to a single fuse but that circuit splits to many modules such as keyless entry, clock, power doors-seats, etc, etc and I would need to remove the interior to troubleshoot-not worth it. It can go for about 2 weeks before it won't start. I never understood why it needed a new battery every few years but the drain was ruining the battery by it being partially discharged all the time. My solution is a battery tender plugged into the ceiling with the plug hidden in the grill. Problem with battery disconnect is a lot of things need to be relearned everytime.

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Tony H
W111 280SE 3.5 Coupe
Manual transmission

Past cars:
Porsche 914 2.0
'64 Jaguar XKE Roadster
'57 Oval Window VW
'71 Toyota Hilux Pickup Truck-Dad bought new
'73 Toyota Celica GT