Hello Gang! One of you will surely have an answer to this:

On my 2005 E320, with Bi-Xenon headlights:
615 BI-XENON HEADLICHT W.ACTVIE CURVELIGHT RIGHT-DRIVE

With bulbs out on both sides, I've recently replaced both Xenon low beams and the halogen (H7) high beam bulbs. All four working. But, along the way:

Both of the tiny bulbs within the high beam 'canisters' are dead. Pelican forum notes call this: the front driving light bulb (this bulb illuminates the high beam capsule) - having removed it, this is a 4.9 W tiny bulb; looks like a '168'.

Can this bulb be replaced with generic LEDs, without throwing any CANbus error? I'm encouraged that there is no error seen with both of the original bulbs dead.
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OK - Answering my own question here: No, the LEDs are a no-go. They flash intermittently - presumably resistance is too low. Replaced with Standard 5W incandescents.

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'83 300 SD
'05 E320 4Matic
'06 BMW 530 xi
'68 Triumph TR 250 - The only car I ever loved more than the Mercedes; who needs electricity, anyway? - Damn, why did I sell it?!
'59 Jaguar 3.4 'Le Chat Noir' - Damn, why did I sell it?!

It's difficult to make predictions, especially about the future.
- Niels Bohr

Many modern cars use PWM drivers for daytime running lights or indicators. LED's do NOT appreciate having their power turned on and off rapidly and will either strobe or flash. Given that the original bulbs lasted ~20 years, slap a set of incandescents in for a couple bucks and consider it job done.

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Current stable:
1995 E320 157K (Nancy)
1983 500SL 125K (SLoL)

Gone but not forgotten:
1986 300SDL (RIP)
1991 350SD
1991 560SEL
1990 560SEL
1986 500SEL Euro (Rusted to nothing at 47K!)

Gone and wanting to forget:
1985 524TD 167K (TotalDumpster™) [Definitely NOT a Benz]